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3.3.4 Leptin and ghrelin Leptin is a recognized hormone that enhances satiety and energy expenditure, primarily produced by adipocytes [52]

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Musculoskeletal system Disorders associated with the musculoskeletal system often cause painful swelling and permanent damage in the joints of the body, especially the hips, knees and thumbs

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The primary endpoint of this substudy was changes in the psoas muscle (surrounding the spine and linking to the upper pelvis) which decreased by 9.3% (95% CI: 13.4 to 5.2