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The surface modification of blood exosomes with transferrin-conjugated superparamagnetic nanoparticles via interaction with the transferrin receptor, with L17E endosomolytic peptides (IWLTALKFLGKHAAKHEAKQQLSKL) via electrostatic interactions, and with cholesterol-conjugated miR-21 inhibitor by anchoring to the lipid membrane increased tumor accumulation and drug delivery and enabled efficient endosomal escape 40

Acknowledgments This study was supported by a grant from the National Leading Research Laboratory (NRF-2015R1A2A1A05001832) and a grant from the Basic Science Research Program (NRF-2015M3A9E2030125) through the National Research Foundation of Korea (NRF), funded by the Ministry of Science, ICT, & Future Planning, Korean Government

doi: 10.1093/nar/gkr988 168 XiaJSinelnikovIVHanBWishartDS