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Conversely, reduced diversity is associated with an elevated risk of inflammatory bowel disease, obesity, type 2 diabetes, cardiovascular disease, and certain cancers 49

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Without enough choline, fat metabolism may become less efficient

Receptor Structure and Activation ERRs share the typical nuclear receptor domain structure, with an N-terminal activation domain, a central DNA-binding domain, and a C-terminal ligand-binding domain (LBD)

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