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It has been confirmed that patients with T2DM have a higher risk of developing NDD, including AD, PD, amyotrophic lateral sclerosis and Huntingtons disease, which in these patients are accompanied by more pronounced motor deficits and faster disease progression

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Moreover, SARS-CoV-2 infection may damage the choroid plexus epithelium, leading to leakage of immune cells and cytokines into the cerebrospinal fluid (CSF) [36, 44]

Experiments were repeated three times independently, with similar results( a-m )

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