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These metrics are more sensitive than weight at low doses because appetite changes often precede measurable weight changes by weeks

Severe gastrointestinal conditions Semaglutide slows digestion and may worsen symptoms in individuals with underlying gastrointestinal issues

A lower mRS score means the patient is more independent

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Neurones depend on glial cysteine for glutathione synthesis as they lack the trans-sulphuration pathway which in turn results in them being more susceptible to oxidative stress [40]

The HR for the expanded MACE outcome was similar to that of the primary outcome (HR 0.82