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28 "Based on this pharmacovigilance study, GLP-1RAs, except albiglutide, are associated with pancreatic carcinoma," researchers noted, adding, "Based on the bibliometric investigation, cAMP/protein-kinase, Ca2+ channel, endoplasmic-reticulum stress, and oxidative stress are potential pathogenesis of pancreatic carcinoma resulting from GLP-1RAs." 29 The kidneys also seem to be negatively affected, with two case studies showing acute kidney injury in people taking semaglutide

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Contact your healthcare provider immediately if you notice unusual symptoms, such as a severe headache, vision changes, excessive bruising or bleeding, or allergic reactions, such as a rash or swelling

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(2011) Evidence for proteolysis of a recombinant prion protein in a lamb brain-amended loamy soil Eur