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Therefore, the pooled effect estimates presented in this review should be considered preliminary and warrant confirmation in future, larger-scale studies

Considering the low rate of patient dropout (almost 12% in the L-carnitine group and 10% in the placebo group), to prevent a biased comparison, all analyses were performed on an ITT analysis dataset [29]

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When calculated as a proportion relative to total body weight, participants in the placebo group experienced a reduction in soft lean tissue mass of 0.8% compared to those in the semaglutide arm who gained 5.5% of lean soft tissue mass relative to total body weight