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With respect to definition of controls, most studies recruited healthy children with no information about family history of autism spectrum disorders, although, four studies did ensure that controls did not have either a family history or sibling with autism [70, 75, 77, 87] and one screened for autism traits [59]

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"Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial"

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Narrow margin between therapeutic dose and toxic dose

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