One observed a positive association between liraglutide use at 12 weeks and improved MMSE in 47 adults with T2DM, which correlated with increased task (verbal fluency)-based activation of the dorso-lateral prefrontal and orbitofrontal cortex, while several other cognitive tests were not affected 45
Factors affecting real-world results include dosing adjustments for side effects, adherence challenges, and less intensive lifestyle support than in trials
And about 10% achieved 25% or greater, representing the super-responders
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Semaglutide is a peptide, and peptides degrade when exposed to heat, light, or contamination

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