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Obesity-related asthma individuals have worsened asthma severity [25, 26], symptom burden [19, 27], the highest healthcare utilization rates [28, 29], reduced effectiveness of conventional therapies [30, 31], and different metabolic signatures [32], compared to individuals that are normal-weight and diagnosed with asthma
Early trial data for the pill has shown improvements in: Blood pressure Lipid markers Insulin sensitivity Waist circumference But healthcare providers will likely continue evaluating long-term cardiovascular outcomes before considering the evidence equally mature
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References 1 Growth Hormone & IGF ResearchLong-Arg3-IGF-1: structure, reduced IGF binding-protein affinity, and extended biological activity of the analog
Antimicrob Agents Chemother 42(12):30733078 Kumar A, Kumar A (2015) Role of Staphylococcus aureus virulence factors in inducing inflammation and vascular permeability in a mouse model of bacterial endophthalmitis
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