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Over timeparticularly as patients transition from the active-weight-loss phase to long-term maintenancethe psychological burden of ongoing injections can become more apparent, Akshay Jain, a clinical instructor at the University of British Columbia, told me

Neither drug should be used by patients with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)

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It is administered subcutaneously at a dose of 200500 mcg, typically before bedtime