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These polyps can rupture and bleed

Melanocytes treated with curcumin (an Nrf2 inducer) showed a reduced apoptosis and high level of NQO-1 Nrf2-target genes (Elassiuty et al., 2011

Additionally, this study was limited by a follow-up duration of only 12 months and was conducted at a single center, rather than multiple centers

You can also search for UK-based studies via the NIHR Be Part of Research platform (bepartofresearch.nihr.ac.uk), the ISRCTN registry (isrctn.com), or ClinicalTrials.gov for multinational trials