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CNTF: ciliary neurotrophic factor) Melanocortin receptor signaling Recent evidence indicates the single-minded homologue 1 (SIM1) transcription factor acts as a proximal mediator for the anorectic, but not thermogenic, effects of melanocortins [67]

Erysipelatoclostridium relative abundance was significantly greater in the vehicle-treated group switched from WD to LD relative to all other groups (before FDR correction, Fig

However, DIO mice switched from an obesity-promoting WD to an LD (regardless of treatment status) displayed several genera and phyla differences compared to obese and lean controls

Cecal levels of Erysipelatoclostridium abundance have been positively correlated with dyslipidemia 93 , and a report that WD decreased the relative abundance of Erysipelatoclostridium and that the abundance of Erysipelatoclostridium negatively correlated with obesity-related indices 90 may partially explain our observation that decreased levels of Erysipelatoclostridium were present in the 5A-1MQ-treated group and the WD control group relative to the vehicle-treated group switched from WD to LD

Exploration of compounds influencing body composition at a cellular level

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