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Our later studies on the Shank3 -/- and Cntnap2 -/- knockout mice, the human SH-SY5Y cell line, and the human induced pluripotent stem cellsderived cortical neurons isolated from patients carrying a SHANK3 mutation confirmed the increased levels of NO and protein SNO [172,173,174,175,176]

Here, "reduced" refers to a reducing agent, which stands in opposition to an oxidizing agent

[DOI] [PMC free article] [PubMed] [Google Scholar] 21.Bilic M., Bumber Z., Blagaic A.B., Batelja L., Seiwerth S., Sikiric P

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Among these brain regions, the PVN exhibited the highest number of EGFP + /MOR + cells (Fig