Finally, current limitations and future prospects are proposed, with the aim of providing inspiration for targeted readers in the field
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Multiple stem cell lineages, including germline stem cells (GSCs) [268], embryonic stem cells (ESCs) [267, 268], neural stem cells (NSCs) [268], hematopoietic stem cells (HSCs) [269], mesenchymal stem cells (MSCs) [270], epidermal stem cells (EpSCs) [271], induced pluripotent stem cells (iPSCs) [267] and organoid stem cells [267], have been reported to undergo ROS-mediated regulation, thereby influencing cell fate
The age-related hormonal changes also contribute to these disorders, while sedentary lifestyles and obesity exacerbate the risk