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A 2026 study showed that coffee consumption changes the gut microbiome in a way that decreases GABA-producing bacteria.[ref] Conditions linked to altered GABA: Altered GABA levels in the brain and central nervous system can lead to several different psychological disorders through either too much inhibition or not enough inhibition of neurons

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Kinetic assays for tissues or cells provide deeper insights, aiding diagnosis in conditions like anemia

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