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A meta-analysis of 113 RCTs comprising 33,167 patients in the GLP-1 RA cohort and 26,683 in the comparator cohort revealed no significant elevation in pancreatitis or pancreatic cancer risk relative to control groups (Mantel-Haenszel odds ratio [MH-OR] of 0.93 and 0.94, respectively), but identified a notable increase in cholelithiasis risk (MH-OR, 1.30) [58]

Reordering adds both direct cost and research timeline disruption

The American Diabetes Association recommends regular blood pressure monitoring and medication titration to maintain blood pressure targets while avoiding symptomatic hypotension

GLP-1 medications work by mimicking a hormone that is naturally produced by our small intestine, called GLP-1 (short for glucagon-like peptide 1)

Once people stop taking these drugs, most seem to regain their lost weight