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Holtkamp N, Okuducu AF, Mucha J, Afanasieva A, Hartmann C, Atallah I, et al

Overall, the data imply that imbalances in oxidative stress markers and antioxidant capacity may contribute to muscle pain and loss in patients with FM [25]

Hypertrophic adipocytes can promote the infiltration of macrophages into adipose tissue, thereby creating a local microenvironment characterized by a pro-inflammatory state, manifested by increased production of various cytokines, including tumor necrosis factor- (TNF-), interleukin-6 (IL-6), and chemokines

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