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Researchers are currently investigating whether using GLP-1s leads to a higher proportion of lean mass loss, but the available evidence suggests that people who lose weight while using GLP-1s can still maintain or even improve their muscle function

Thillainadesan S, Madsen S, James DE, Hocking SL

Triplehormonereceptor agonist retatrutide for obesitya phase 2 trial

Efficacy and safety of the novel triple agonist retatrutide in type 2 diabetes. NEJM , 2023

Oral GLP-1 therapies can expand the market, but they may not completely overtake injectables

En ambos casos, aproximadamente el 5-10% de pacientes pierden menos del 5% de su peso corporal, incluso con dosis adecuadas