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Oxidative stress induces the dissociation of the NRF2-Keap1 complex When cells undergo oxidative stress, ionizing radiation, or chemical stimulation, it may lead to the generation of reactive oxygen species (ROS) or reactive oxygen free radicals within the cells, triggering an oxidative stress response

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Studies indicate that semaglutide can lead to significant weight loss and improved hormonal regulation in women with PCOS, although more research is needed to understand its effects fully