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Similarly, the concomitant downregulation of Adam19, a metalloproteinase closely associated with inflammation and oxidative stress-induced tissue remodeling 56 , further reinforces the hypothesis that APP treatment actively promotes endogenous antioxidant defenses and improves redox homeostasis rather than provoking nonspecific oxidative damage

Sakhi, Amrit Kaur, et al

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Emerging tools, such as pharmacogenetic (110) and nutrigenomic (111) tests now facilitate large-scale pharmacogenomic and nutrigenomic analyses, enabling the early identification of genetic variants that affect nutraceutical-drug interactions

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