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Patients frequently experience: Fatigue and generalised weakness that persists despite adequate rest Breathlessness on exertion due to anaemia Palpitations and reduced exercise tolerance Pallor of the skin and mucous membranes These symptoms result from megaloblastic anaemia, where impaired DNA synthesis leads to the production of abnormally large, dysfunctional red blood cells with reduced oxygen-carrying capacity
For example, if the initial benefits wane, the dosage or frequency of injections may need to be adjusted
Higher doses and shorter durations fit acute healing
Introduction ERR (ESRRA), ERR (ESRRB), and ERR (ESRRG) are orphan nuclear receptors closely related to classical estrogen receptors but with distinct transcriptional networks
Consistency often matters more than intensity