Pre-clinical research conducted primarily in animal models informs the hypotheses for its use, but no large randomized controlled trials in humans have confirmed efficacy for any outcome - including gut-lining support, tissue-related processes, or any other claimed mechanism
Overall, it appears the side effects of Mounjaro versus Ozempic are largely comparable
Plaintiffs had also raised concerns that the early discovery process could put the NAION litigation out of sync with Marstons separate GLP-1 stomach paralysis MDL, which involves thousands of cases and is proceeding toward its own independent bellwether process
FIGURE 1 2.2 GSHs role in brain-resident immune cells In the CNS, GSH protects mitochondrial function, prevents lipid peroxidation, and maintains the redox state of cysteine residues in proteins
Regulatory/ethical issues
So, Jitania, I think that policy backdrop really ties directly to your idea of the age of capped real rates