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Semaglutide and Facial Aging: Common Concerns Many patients notice changes such as: Semaglutide loose skin Semaglutide and facial volume loss Semaglutide aging face Semaglutide and under eye hollows These concerns often stem from the bodys inability to regenerate collagen and elasticity at the same pace as the fat loss, especially in the face

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These observations were interpreted as potentially consistent with altered photoreactivity, though inter individual variability and study design limitations were noted as relevant considerations

10.1016/S0140-6736(21)01324-6 38 SvendsenB.HolstJ