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(c) Representative image of positive SMAD6 staining in vascular endothelial cells (arrows) and macrophages (arrowheads)

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Its clinical signs include insensitivity and excruciating neuropathic pain, which raises the possibility of burns, wounds, and foot ulcers

Any unusual symptoms should be reported to your healthcare provider

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doi: 10.1017/S0033291713000020 549 WilshireCEKindlonT