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Constipation may allow the medication to sit in the body longer and be absorbed more, [while] vomiting and diarrhea may rid the body of the medication [more] quickly before it has time to reach its maximal effect. Finally, although your body weight wont affect the metabolism of Wegovy, your overall body mass index (BMI) and muscle tissue can play a part

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Fiber adds bulk and expands in the gut, which can create a painful blockage in a digestive system that has already been slowed down by weight-loss medication

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doi: 10.1016/j.jid.2024.11.007 17 TangFLiSLiuDChenJHanC