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What started as a diabetes and weight-loss therapy is now a potential tool against chronic inflammation, liver damage, and heart disease

The gastrointestinal side effects common with GLP-1 medications compound this problem significantly

A 2022 randomized trial of exenatide did not meet its primary endpoint for reducing heavy drinking days in the overall population, though exploratory analyses suggested potential benefits in participants with obesity

Two edge cases deserve explicit framing

This review explores the mechanisms, clinical development, and therapeutic potential of these novel agents, excluding already approved drugs like liraglutide, semaglutide, and tirzepatide

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