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The structural differences are real

10.1016/j.bbi.2020.10.014 98 SunH.ShuJ.TangJ.LiY.QiuJ.DingZ.et al (2024)

Then the SELECT cardiovascular outcomes trial added a 20% reduction in major adverse cardiovascular events in overweight and obese patients with established heart disease independent of diabetes status, and partially independent of the weight loss itself

The water avoidance stress induces bladder pain due to a prolonged alpha1A adrenoceptor stimulation

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