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Structurally, the molecule is based on GIP backbone with a number of amino acid substitutions tuning the affinity for each of the three receptors and on acylation with a fatty acid chain (C20)

Results CB0313.1 improves hyperglycemia and insulin resistance in lep db/db Mice db/db To test the effects of CB0313.1 on glucose homeostasis, we performed oral glucose (OGTT) and insulin (ITT) tolerance tests

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Hydropersulfides were found to be excellent H-atom donors to radicals, including alkyl, alkoxyl, peroxyl and thiyl radicals 31