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The body is adapting to lower energy intake
Acta Biomaterials, 115 , 92103
In addition, CagriSema led to a greater proportion of participants able to decrease or stop treatment with antihypertensive medications compared with placebo and other monotherapies
Liang CJ, Yen YH, Hung LY, Wang SH, Pu CM, Chien HF
The peptides hormonal relevance remains theoretical and based on its effects on upstream factors (inflammation, vascular health, gut integrity) rather than direct HPG axis stimulation
This metabolic improvement occurs through AMPK pathway activation and increased NAD+-dependent SIRT1 activity, both of which enhance insulin receptor signaling and glucose metabolism
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