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In phase 2 clinical trials conducted in adult populations, retatrutide demonstrated substantial weight-loss efficacy, with reported reductions of up to 24.2% over a 48-week treatment period

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The highest dose of retatrutide helped patients lose 28.3% of their weight or 70.3 pounds on average over 80 weeks, compared with 2.2% with placebo, when evaluating only patients who stayed on the drug

Women may experience more variable results month to month due to hormonal fluctuations across the menstrual cycle