Hyperglycaemia impairs immune function , particularly neutrophil activity and cell-mediated immunity, making individuals with poorly controlled diabetes more prone to bacterial and fungal infections
Metformin: In clinical trials for obesity and type 2 diabetes, metformin is sometimes used alongside GLP-1-based agents under medical direction
F4/80, a monoclonal antibody directed specifically against the mouse macrophage
Severely restricting calories accelerates muscle loss, tanks your metabolism, depletes micronutrients, crashes energy levels, and sets you up for a massive rebound when appetite eventually returns
The patterns are predictable, and preparation goes a long way
The Step 1 protocol is discussed only if clinically appropriate for your profile