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On one hand, a retrospective cohort study demonstrated a significant protective association, linking GLP-1RA use to a reduced risk of nonexudative AMD, with an efficacy reported to be superior to that of metformin, insulin, and statins [111]

oral regimens), and trial endpoints better tuned to metabolic mechanisms

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This titration could look something like this: Start with 1 mg weekly via subcutaneous injection

23 Three studies presented some concerns related to lack of blinding (ESM eFig

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