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3,4 The first official diagnostic guidelines were published in 1990 by the American College of Rheumatology, followed by treatment guidelines published by the American Pain Society in 2005

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On published endpoints, Novo Nordisk's April 2024 Phase 3 readout in type 2 diabetes reported a 14.2% mean body-weight reduction at 68 weeks for CagriSema 2.4mg/2.4mg from a 101kg baseline, versus 10.2% for semaglutide 2.4mg alone [4]

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