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Manifest hair repigmentation associated with etretinate therapy

Volunteer pairs were recruited when the children were born and then tracked for up to 15 years

Notably, the overlap between PCS-CFS and T2bFA-CFS was more pronounced at the level of core transcriptional programs ( Figure 2B ) than at the pathway level ( Figure 2C ), indicating that shared mitochondrial repression may be accompanied by context-specific secondary remodeling programs

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Activation of the receptor leads to stimulation of the Gq/11 protein-dependent pathway, an increase in IP3 concentration, the release of calcium ions from the endoplasmic reticulum and, consequently, the exocytosis of GH-containing granules