International Journal of Endocrinology, 2018 , 4847376
Shahoei, S
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While medication alone wont solve this global health crisis, GLP-1 therapies can help millions overcome obesity and reduce its associated harms. The WHO did qualify its recommendations, saying endorsement is conditional due to limited data on their long-term efficacy and safety, maintenance and discontinuation, their current costs, inadequate health-system preparedness, and potential equity implications. The drugs should not be used by pregnant women, and should be paired with evidence-based interventions like healthy diets and physical activity, the guidelines also stress
As initial appetite suppression fades, portion sizes may unconsciously increase, or food choices may drift from the structured eating patterns that supported early weight loss
Bruls YM, de Ligt M, Lindeboom L, Phielix E, Havekes B, Schaart G, et al