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Hepatology 71 , 16781695 (2020)

Clinical trials and post-marketing surveillance have identified a modest increase in resting heart rate as a potential effect of GLP-1 receptor agonists

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Considerations: As with any copper-containing compound, there is a theoretical concern about copper toxicity with excessive systemic administration

The mitochondrial AsA-GSH cycle deals with both photosynthetic as well as stress-induced oxidative stress (Jimenez et al., 1997)

For most patients starting fresh without strong factors favoring one medication, I lean toward Tirzepatide given the superior efficacy and tolerability data