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The peptide activates HGF/c-Met signaling cascades that upregulate synaptogenesis, dendritic spine growth, and NMDA receptor expression, and these changes continue autonomously once triggered

Available online at: [Accessed April 14, 2025]

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Ipamorelin, as a peptide, has been subject to evolving FDA policy discussions regarding Category 1 and Category 2 503A classification, though its current status places it outside the list of office-compoundable bulk drug substances without an active investigational new drug application