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Manifestations possibles : douleur locale au point de perfusion, ecchymose post-retrait cathter, cphales transitoires (dshydratation), nauses lgres (perfusion trop rapide), got mtallique (vitamines B)

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Have used or now use illegal injectable drugs

Rotate injection sites across the abdomen

2015;98(Suppl 9):S23-30

Transdermal estradiol patches or gels rather than oral estrogen, which avoids first-pass liver metabolism and reduces effects on factor XII and the kallikrein-kinin system implicated in angioedema