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Methylcobalamin Methylcobalamin is a naturally occurring, bioactive form of vitamin B12 that the body can use immediately

UK guidance (MHRA and NICE) advises checking B12 levels in patients on metformin who develop symptoms of deficiency (anaemia, neuropathy) and considering periodic monitoring in those on long-term therapy

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In preclinical models, its applied to cultured fibroblasts, epithelial tissues, and immune cells to study telomere dynamics, cell-cycle checkpoints, and oxidative-stress defensesall key processes in cellular aging

1a,b and Extended Data Table 1)