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Health 24 , 447490 (2008)

10.1016/j.bbi.2020.07.015 37 El HajjS.Canabady-RochelleL.GaucherC

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This finding agrees with the literature whereby the role of quinone redox metabolism is an ambiguous source of toxicity, with evidence suggesting that redox cycling requires supra-pharmacological concentrations of doxorubicin to generate substantial ROS in tissues and cells 10