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In lung cancer, particularly NSCLC, reduced GAS5 expression is associated with advanced TNM stage and larger tumor volume

In some embodiments, the otic formulation or composition comprises between about 0.01% to about 40% by weight of the poloxamer

Adipose tissue remodeling ERR-dependent programs in adipose tissue intersect with thermogenesis, lipolysis, and adipocyte mitochondrial function

However, these methods are usually only applicable to small molecule compounds based on passive diffusion through BBB

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