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Indeed, it has been suggested that agents capable of achieving an average weight reduction of about 15% in individuals with obesity represent a new generation of anti-obesity medications, as this level of weight loss is sufficient to combat or prevent a broader range of obesity-related complications (238)

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These cellular transformations contribute significantly to enhanced endurance during exercise, thereby underscoring the critical role that GLP-1 plays in the regulation of mitochondrial function and content in skeletal muscle

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