It is involved in the oxidative metabolism of many endogenous substances such as steroids and bile acids, as well as the detoxication of a wide variety of xenobiotics

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Tzveova R, Naydenova G, Yaneva T, Dimitrov G, Vandeva S, Matrozova Y, et al
Petrochenko, P
Many patients with an overactive thyroid gland experience weight loss relative to the severity of the over-working thyroid
Medical Pharmacology Chapter 2: General Principles: Pharmacokinetics Cytochrome P450 Enzyme Induction: Following repeated administration, some drugs increase the amount of P450 enzyme usually by: Increase enzyme synthesis rate (induction) Reduced enzyme degradation rate Cytochrome P450 enzyme inhibition: Certain drugs, by binding to the cytochrome component, act to competitively inhibit metabolism