First, radiation activates the cGAS-cGAMP-STING pathway in the body, which results in the recruitment of macrophages to the site of radiation damage, leading to inflammation and fibrosis 46
[PubMed: 36883831] Garvey WT, Blcher M, Osorto Contreras CK, et al
Acknowledgements This work has been supported by National Natural Science Foundation of China grants (W2412122, 82470195, 82200208), Natural Science Foundation of Tianjin grants (24JCYBJC00780, 24ZXZSSS00050), State Key Laboratory of Druggability Evaluation and Systematic Translational Medicine grants (QZ 23-6, 23-4), Jin Men Medical Talents of Tianjin (TJSJMYXYC-D2-039), Clinical Oncology Research Fund of CSCO grant (Y-2024AZ(BTK)MS-0040) and Tianjin Key Medical Discipline (Specialty) Construction Project grant (TJYXZDXK-009A)
& El Andaloussi, S
10.1038/emboj.2012.65 EMBO J
Related Health Issues Pulmonary embolisms (blood clots, fat globules, etc) Addictions Seizures Miscarriages Mental health issues (such as severe depression and schizophrenia) Cancer Autism Spina bifida Glaucoma Migraines Developmental delay Fibromyalgia Researchers are hopeful that current, ongoing studies will provide the answers
