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10.1053/j.gastro.2017.08.028 Gastroenterology

Therefore, our studies add novel insights into a growing body of evidence implying that a combination of virus and host factors such as residual immune activation, hematopoietic dysregulation, and autoimmune phenomena could contribute to LC syndrome

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Auranofin shows an additive effect with COJEC chemotherapy Because the antagonism observed between RSL3 and COJEC appears to be mediated by GPX4 upregulation, we decided to test COJEC in combination with a ferroptosis-inducing agent with a different MOA, the TrxR inhibitor Auranofin