For patients concerned about cellular oxidative stress during weight loss, nutritional approachessuch as consuming antioxidant-rich vegetables, berries, and green teamay provide similar benefits at lower cost than supplemental glutathione
Clinical outcomes may vary due to individual biological differences
Some options are designed to reach higher maintenance doses to maximise appetite suppression, while others prioritise gradual escalation to improve tolerability
This review comprehensively summarizes the role of mitophagy in metabolic diseases, the effects of different types of exercise on mitophagy, and the potential mechanisms of exercise-regulated mitophagy intervention in metabolic diseases, providing new insights for basic and clinical research on exercise intervention for preventing and treating metabolic diseases
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Liver-expressed antimicrobial peptide 2 (LEAP-2), the endogenous noncompetitive allosteric antagonist of the growth hormone secretagogue receptor 1a (GHSR1a), was recently identified as a key endocrine factor regulating systemic energy metabolism