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Cell-based assays and in vitro systems are used by scientists to study the binding properties, structural stability, and signaling activity under controlled conditions

[DOI] [PubMed] [Google Scholar] 45.Reusch J, Stewart MW, Perkins CM, Cirkel DT, Ye J, Perry CR, Reinhardt RR, Bode BW

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Increasing evidence has demonstrated that GLP-1 analogues can cross the blood-brain barrier, protect dopaminergic neurons in the substantia nigra, and rescue motor activity and cognitive functions in PD animal models (5961)

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These include nausea, vomiting, diarrhoea, constipation, dyspepsia, and abdominal pain