We continue to believe it is appropriate to subject the diagnostic radiopharmaceutical packaging threshold to the same update factor that is used for the OPPS drug packaging threshold as supported by the majority of commenters
And safety data across all human trials was excellent
Some researchers found that VitB12 supplementation is associated with a decrease in sleep duration [15, 21, 22], whereas others found no significant association between VitB12 and sleep duration [23]
Hydroxocobalamin tends to remain in the body longer and is more readily converted to the active coenzyme forms of B, which can make it effective for maintaining B levels
this effect may be due to interference with erythrocyte maturation
Anyone on long-term metformin, PPIs, or a GLP-1 protocol with significantly reduced intake for months should have B12 checked as part of routine monitoring