how does retatrutide work for weight loss VisualAbstract: reduces body by 17.5% in patients with obesity Retatrutide: Understanding the mechanism of

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2019;68[Suppl 1]:244-OR

Tip #2: Watch What You Eat, Especially at First GLP-1 medications slow the movement of food through your gut, which is why most side effects are stomach-related: nausea, heartburn, that heavy "I ate too much" feeling

Then the SELECT cardiovascular outcomes trial added a 20% reduction in major adverse cardiovascular events in overweight and obese patients with established heart disease independent of diabetes status, and partially independent of the weight loss itself

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This process produces compounds called short-chain fatty acids (SCFAs) , which have been shown to stimulate GLP-1 secretion from specialized cells in the gut